Featured Peptides
Sermorelin 5mg | ≥99% Purity | UK Research Peptide
Sermorelin 5mg research peptide (GHRH 1-29), ≥99% purity, HPLC + MS verified. Lyophilised, UK batch-tested. In-vitro research only.
🚚 Free UK shipping over £100 · dispatched next business day ·
- ✓ Independently HPLC + MS verified — per-batch Certificate of Analysis
- ✓ Pay by Bank (Fena / Wallid) or bank transfer (BACS)
⚠ For laboratory research use only. Not for human or veterinary use. Must be 21+ to purchase.
Sermorelin 5mg is a synthetic 29-amino-acid analogue of growth hormone-releasing hormone (GHRH 1-29) supplied as lyophilised powder for laboratory research. Every batch is HPLC-verified to ≥99% purity with identity confirmed by mass spectrometry, and independently tested by an ISO 17025 accredited third-party laboratory. It is supplied strictly for in-vitro research use only.
Sermorelin 5mg at a Glance
| Product | Sermorelin 5mg |
| Quantity | 5mg per vial |
| Form | Lyophilised powder (requires reconstitution) |
| Sequence | Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg-NH2 |
| Molecular formula | C149H246N44O42S |
| Molecular weight | ≈3,357.9 Da |
| CAS number | 86168-78-7 |
| Purity | ≥99% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Testing | ISO 17025 accredited third-party laboratory, batch-specific certificate |
| Storage | Lyophilised: −20°C long term. Reconstituted: 2–8°C |
| Intended use | Research use only. Not for human or veterinary use. |
What Is Sermorelin?
Sermorelin is the amidated 1–29 fragment of human growth hormone-releasing hormone, the shortest fragment that retains full activity at the GHRH receptor. It is the reference GHRH analogue in pituitary research and the compound against which longer-acting analogues such as Tesamorelin and CJC-1295 are compared. Our Sermorelin 5mg vial contains the 29-residue sequence with a molecular weight of approximately 3,357.9 Da.
The lyophilised format keeps the peptide stable in storage and lets researchers reconstitute to the exact concentration their protocol requires. Sermorelin is also available as a 10mg vial for larger study designs.
Sermorelin Research Areas
Laboratory studies of Sermorelin cover the following areas of the published literature:
GHRH Receptor Pharmacology
Sermorelin is used as the reference agonist in GHRH receptor binding and cAMP signalling assays, and as a comparator when characterising modified analogues. Published work can be explored on PubMed.
Pituitary Somatotroph Models
Primary pituitary cell cultures use Sermorelin to study growth hormone synthesis and pulsatile release, and how GHRH signalling interacts with somatostatin and ghrelin-receptor pathways.
Peptide Stability and Degradation
Because the native 1–29 sequence is rapidly cleaved by dipeptidyl peptidase-4, Sermorelin is a common substrate in enzyme-stability studies and a baseline for stabilised analogue design.
Growth Hormone Axis Research
Preclinical models use the peptide to investigate downstream effects of GHRH-driven GH release, including IGF-1 signalling and metabolic markers.
Sermorelin vs Tesamorelin and CJC-1295
All three act on the GHRH receptor. Sermorelin is the unmodified 1–29 fragment; Tesamorelin is a 44-residue analogue with an N-terminal modification for stability; CJC-1295 (No DAC) carries four amino-acid substitutions that resist enzymatic cleavage. Researchers choose Sermorelin when they want native-sequence behaviour, and the modified analogues when a longer-lived signal is required.
Why Researchers Choose Sermorelin 5mg from ThePeptideCode
- Verified purity: ≥99% by HPLC, with identity confirmed by mass spectrometry.
- Independent testing: every batch is tested by an ISO 17025 accredited third-party laboratory.
- Batch-specific certificates: the certificate matches the batch you receive.
- Accurate fill: 5mg of peptide per vial, lyophilised for stability.
- Fast UK dispatch: in-stock items are dispatched within one working day.
- UK Express delivery: £6.99, free on orders over £100.
Quality Control and Batch Testing
Every batch of Sermorelin 5mg is analysed before release. HPLC confirms purity, and mass spectrometry confirms that the peptide mass matches the expected sequence. You can view current certificates on our verification and testing page.
Storage and Handling
Store lyophilised Sermorelin at −20°C for long-term stability, protected from light and moisture. Reconstitute with bacteriostatic water using aseptic technique, then keep the solution refrigerated at 2–8°C and use promptly. See our guides on how to reconstitute peptides and how to store research peptides.
Research Use Only
Sermorelin 5mg is supplied strictly for in-vitro laboratory research. It is not a medicine, supplement or cosmetic product. It is not intended to diagnose, treat, cure or prevent any disease, and it is not for human or veterinary use. By purchasing, you confirm that the product will be used solely for lawful laboratory research.
Sermorelin 5mg FAQs
What is Sermorelin?
Sermorelin is a synthetic 29-amino-acid peptide corresponding to residues 1–29 of human GHRH. It is the reference GHRH-receptor agonist in pituitary and growth hormone axis research.
What is the molecular weight of Sermorelin?
Approximately 3,357.9 Da (molecular formula C149H246N44O42S).
Does Sermorelin 5mg need reconstituting?
Yes. It is supplied as lyophilised powder and should be reconstituted with bacteriostatic water before use in research protocols.
How is Sermorelin 5mg tested?
Every batch is tested to ≥99% purity by HPLC, with identity confirmed by mass spectrometry, at an ISO 17025 accredited third-party laboratory.
How should Sermorelin be stored?
Keep the lyophilised vial at −20°C for long-term storage. Once reconstituted, refrigerate at 2–8°C and use promptly.
Is Sermorelin 5mg for human use?
No. It is supplied strictly for in-vitro laboratory research and is not for human or veterinary use.