Featured Peptides
Cagrilintide 10mg | ≥99% Purity | UK Research Peptide
Cagrilintide 10mg long-acting amylin analogue research peptide, ≥99% purity, HPLC + MS verified. Lyophilised, UK batch-tested. In-vitro research only.
🚚 Free UK shipping over £100 · dispatched next business day ·
- ✓ Independently HPLC + MS verified — per-batch Certificate of Analysis
- ✓ Pay by Bank (Fena / Wallid) or bank transfer (BACS)
⚠ For laboratory research use only. Not for human or veterinary use. Must be 21+ to purchase.
Cagrilintide 10mg is a long-acting, lipidated analogue of human amylin, supplied as a lyophilised powder for laboratory research. Every batch is HPLC-verified to ≥99% purity with identity confirmed by mass spectrometry, and independently tested by an ISO 17025 accredited third-party laboratory. It is supplied strictly for in-vitro research use only.
Cagrilintide 10mg at a Glance
| Product | Cagrilintide 10mg |
| Peptide content | 10mg per vial |
| Class | Long-acting amylin analogue; dual amylin and calcitonin receptor agonist (DACRA) |
| Structure | 37-amino-acid human amylin backbone with N14E, V17R and P37Y substitutions, C-terminal amide, Cys2–Cys7 disulfide bridge, and an N-terminal lysine acylated with a C20 fatty diacid via a γ-glutamate linker |
| CAS number | 1415456-99-3 |
| Molecular formula | C194H312N54O59S2 (≈4,409 Da) |
| Synonyms | AM833, NNC0174-0833 |
| Form | Lyophilised powder (requires reconstitution) |
| Purity | ≥99% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Testing | ISO 17025 accredited third-party laboratory, batch-specific certificate |
| Storage | Lyophilised: −20°C long term. Reconstituted: 2–8°C |
| Intended use | Research use only. Not for human or veterinary use. |
What Is Cagrilintide 10mg?
Cagrilintide is a synthetic analogue of amylin (islet amyloid polypeptide), the 37-amino-acid hormone co-secreted with insulin by pancreatic β-cells. Native amylin has a plasma half-life of minutes and a strong tendency to aggregate into amyloid fibrils, which limits its use as a research tool. Cagrilintide was engineered (Kruse et al., Journal of Medicinal Chemistry, 2021) to address both problems: three backbone substitutions reduce fibrillation, while a C20 fatty-diacid side chain attached through a γ-glutamate linker promotes reversible albumin binding and extends circulating half-life to around a week in reported pharmacokinetic studies.
Pharmacologically, cagrilintide is a non-selective agonist at amylin receptors (the calcitonin receptor in complex with RAMP1–3, giving AMY1–AMY3) and at the calcitonin receptor itself, which is why it is classed as a dual amylin and calcitonin receptor agonist. Published work can be explored on PubMed.
Cagrilintide 10mg Research Applications
Cagrilintide 10mg is typically investigated in laboratory settings such as:
- Receptor pharmacology: cAMP and β-arrestin assays at calcitonin receptor and CTR–RAMP amylin receptor complexes, and selectivity profiling across the AMY1–AMY3 subtypes.
- Peptide stability and albumin binding: plasma-stability and albumin-affinity assays comparing the acylated analogue with native amylin or pramlintide.
- Fibrillation studies: thioflavin-T aggregation kinetics and related assays examining how the backbone substitutions suppress amyloid formation.
- Metabolic signalling models: preclinical studies of amylin-receptor signalling in energy-balance pathways, including co-administration designs with GLP-1 receptor agonists.
Researchers working on metabolic peptides may also want our mitochondrial peptides MOTS-c 10mg and SS-31 10mg, or the small-molecule metabolic compound 5-Amino-1MQ 50mg.
Why Researchers Choose Cagrilintide 10mg from ThePeptideCode
- Verified purity: ≥99% by HPLC, with identity confirmed by mass spectrometry.
- Independent testing: every batch is tested by an ISO 17025 accredited third-party laboratory.
- Batch-specific certificates: the certificate matches the batch you receive.
- Full 10mg per vial: accurately weighed, lyophilised in a sealed vial.
- Fast UK dispatch: in-stock items are dispatched within one working day.
- UK Express delivery: £6.99, free on orders over £100.
Quality Control and Batch Testing
Every batch of Cagrilintide 10mg is analysed before release. HPLC confirms purity and mass spectrometry confirms the peptide is present at the expected mass. You can view current certificates on our verification and testing page.
Storage and Handling
Store the lyophilised vial at −20°C for long-term stability, protected from light and moisture. Reconstitute with bacteriostatic water using aseptic technique, swirling gently rather than shaking, then keep the solution refrigerated at 2–8°C and use promptly. Lipidated peptides can be slower to dissolve than short peptides, so allow the vial to reach room temperature before reconstituting. See our guides on how to reconstitute peptides and how to store research peptides.
Research Use Only
Cagrilintide 10mg is supplied strictly for in-vitro laboratory research. It is not a medicine, supplement or cosmetic product. It is not intended to diagnose, treat, cure or prevent any disease, and it is not for human or veterinary use. By purchasing, you confirm that the product will be used solely for lawful laboratory research.
Cagrilintide 10mg FAQs
What is cagrilintide?
Cagrilintide is a synthetic, lipidated analogue of the hormone amylin, engineered for extended half-life and reduced fibrillation. It acts as an agonist at both amylin and calcitonin receptors.
Is cagrilintide a GLP-1 receptor agonist?
No. Cagrilintide acts on amylin and calcitonin receptors, a separate signalling pathway. It is frequently studied alongside GLP-1 receptor agonists in preclinical research because the two pathways are complementary.
Does Cagrilintide 10mg need reconstituting?
Yes. It is supplied as lyophilised powder and should be reconstituted with bacteriostatic water before use in research protocols.
How is Cagrilintide 10mg tested?
Every batch is tested to ≥99% purity by HPLC, with identity confirmed by mass spectrometry, at an ISO 17025 accredited third-party laboratory.
How should Cagrilintide 10mg be stored?
Keep the lyophilised vial at −20°C for long-term storage. Once reconstituted, refrigerate at 2–8°C and use promptly.
Is Cagrilintide 10mg for human use?
No. It is supplied strictly for in-vitro laboratory research and is not for human or veterinary use.
⚠ For laboratory research use only. Not for human or veterinary use, diagnostic, or therapeutic purposes. Must be 21+ to purchase. Handle in accordance with good laboratory practice.