5-Amino-1MQ 50mg Research Grade | NNMT Inhibitor | 99%+ Purity

5-Amino-1MQ 50mg Research Grade | NNMT Inhibitor | 99%+ Purity

5-Amino-1MQ (5-amino-1-methylquinolinium) is a selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT). It is supplied as 50mg research-grade powder at high purity for advanced laboratory investigation into metabolic regulation, adipose tissue biology, NAD+ pathways, and related cellular processes.

Key Details

• Quantity: 5-Amino-1MQ 50mg per vial
• Form: Lyophilized / crystalline powder
• Purity: ≥99% (HPLC verified)
• Intended Use: For research purposes only — not for human consumption, diagnostic, therapeutic, or any other non-laboratory use.

Legal Notice / Disclaimer NOT FOR HUMAN OR ANIMAL CONSUMPTION. This product is strictly intended for in vitro and in vivo laboratory research use only by qualified professionals. It is not approved for human or veterinary use, ingestion, injection, or any form of consumption. Any other use is strictly prohibited. The manufacturer, supplier, and distributors assume no liability for misuse. Handle with appropriate laboratory safety protocols.

Chemical Compound Information

• Chemical Name: 5-Amino-1-methylquinolinium (often as iodide or chloride salt)
• Synonyms: 5-Amino-1MQ, 5A1MQ, NNMT inhibitor
• Molecular Formula: C₁₀H₁₁N₂⁺ (cation); salt-dependent (e.g., C₁₀H₁₁IN₂ for iodide)
• Molecular Weight: ~159.21 g/mol (cation); ~286.11 g/mol (iodide salt)
• Classification: Small-molecule enzyme inhibitor / quinolinium derivative
• CAS Number: 42464-96-0

Area of Interest Laboratory studies of 5-Amino-1MQ have investigated a variety of promising areas:

• Metabolic Regulation & Obesity: Studied as a potent NNMT inhibitor that modulates adipose tissue metabolism, reduces lipogenesis, and supports fat oxidation in preclinical models.
• NAD+ Pathway & Cellular Energy: Explored for preserving nicotinamide availability for NAD+ synthesis, potentially elevating cellular NAD+ levels and activating SIRT1.
• Mitochondrial & Muscle Health: Investigated for effects on muscle regeneration, mitochondrial function, and metabolic health in aging and injury models.
• Inflammation & Related Disorders: Research into impacts on hepatic steatosis, insulin sensitivity, and metabolic dysfunction.

Technical Specifications

• Quantity: 50mg
• Form: High-purity research powder
• Purity: ≥99% (HPLC)
• COA: Provided with each batch (includes HPLC chromatogram and identity confirmation)

Storage Guidelines

• Store at −20°C for long-term stability (sensitive to moisture, heat, and light).
• Protect from humidity and light exposure.
• For reconstituted solutions, follow protocol-specific stability guidelines.

Solubility 5-Amino-1MQ is soluble in DMSO, methanol, and aqueous buffers (solubility varies by salt form; limited in water for some forms).

References 5-Amino-1MQ is a key research tool in NNMT inhibition, metabolic science, and NAD+ biology. Extensive peer-reviewed preclinical literature is available. Contact us with any research-specific questions. Full batch Certificate of Analysis is available upon request.

This matches the established format with the added legal notice. Let me know the next one!