Research Compounds
5-Amino-1MQ 50mg | ≥99% Purity | UK Research Compound
5-Amino-1MQ 50mg NNMT inhibitor research compound, ≥99% purity, HPLC + MS verified. Small-molecule powder, UK batch-tested. In-vitro research only.
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- ✓ Independently HPLC + MS verified — per-batch Certificate of Analysis
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⚠ For laboratory research use only. Not for human or veterinary use. Must be 21+ to purchase.
5-Amino-1MQ 50mg is a small-molecule nicotinamide N-methyltransferase (NNMT) inhibitor supplied as powder for laboratory research. Every batch is HPLC-verified to ≥99% purity with identity confirmed by mass spectrometry, and independently tested by an ISO 17025 accredited third-party laboratory. It is supplied strictly for in-vitro research use only.
5-Amino-1MQ 50mg at a Glance
| Product | 5-Amino-1MQ 50mg |
| Quantity | 50mg per vial |
| Form | Powder (requires dissolution) |
| Chemical name | 5-Amino-1-methylquinolinium (supplied as the salt form stated on the batch certificate) |
| Molecular formula | C10H11N2+ (cation) |
| Molecular weight | ≈159.2 Da (cation); ≈286.1 Da as the iodide salt |
| Purity | ≥99% (HPLC) |
| Identity | Confirmed by mass spectrometry |
| Testing | ISO 17025 accredited third-party laboratory, batch-specific certificate |
| Storage | −20°C long term, protected from light and moisture |
| Intended use | Research use only. Not for human or veterinary use. |
What Is 5-Amino-1MQ?
5-Amino-1MQ (5-amino-1-methylquinolinium) is a quinolinium compound that inhibits nicotinamide N-methyltransferase, the enzyme that methylates nicotinamide using S-adenosylmethionine as the methyl donor. By blocking that reaction, the compound is used to study how NNMT activity shapes the balance between nicotinamide available for NAD+ salvage and the cellular methylation pool. Unlike most of our range it is a small molecule rather than a peptide, with a cation mass of approximately 159.2 Da.
The 50mg fill is sized for cell-culture dose-response work and enzyme assays. Because the compound is supplied as a salt, the exact molecular weight used for molarity calculations should be taken from the batch certificate.
5-Amino-1MQ Research Areas
Laboratory studies of 5-Amino-1MQ focus on the following areas:
NNMT Enzymology
5-Amino-1MQ is a reference inhibitor in NNMT kinetic assays and in structure–activity studies of quinolinium inhibitors. Published work can be explored on PubMed.
Adipocyte Metabolism Models
Because NNMT is highly expressed in adipose tissue, the compound is used in adipocyte cultures and preclinical models to study lipogenesis, energy expenditure and metabolic gene expression.
NAD+ and Methylation Balance
Researchers use the inhibitor to investigate how sparing nicotinamide from methylation affects NAD+ levels, sirtuin activity and S-adenosylmethionine availability. It is often studied alongside NAD+.
Muscle Stem Cell Models
Preclinical work has examined NNMT inhibition in models of muscle regeneration and satellite-cell function.
5-Amino-1MQ vs Other NNMT Inhibitors
5-Amino-1MQ was among the first cell-permeable, selective NNMT inhibitors characterised in the literature, which is why it remains the common reference compound. Bisubstrate inhibitors developed later show higher potency in enzyme assays but poorer cell permeability, so the two classes are often compared in the same study.
Why Researchers Choose 5-Amino-1MQ 50mg from ThePeptideCode
- Verified purity: ≥99% by HPLC, with identity confirmed by mass spectrometry.
- Independent testing: every batch is tested by an ISO 17025 accredited third-party laboratory.
- Batch-specific certificates: the certificate matches the batch you receive.
- Accurate fill: 50mg of compound per vial.
- Fast UK dispatch: in-stock items are dispatched within one working day.
- UK Express delivery: £6.99, free on orders over £100.
Quality Control and Batch Testing
Every batch of 5-Amino-1MQ 50mg is analysed before release. HPLC confirms purity, and mass spectrometry confirms identity. You can view current certificates on our verification and testing page.
Storage and Handling
Store the sealed vial at −20°C, protected from light and moisture. 5-Amino-1MQ dissolves in water, DMSO and methanol, with solubility depending on the salt form; prepare stock solutions fresh and keep working solutions refrigerated at 2–8°C. See our laboratory handling guide for general practice.
Research Use Only
5-Amino-1MQ 50mg is supplied strictly for in-vitro laboratory research. It is not a medicine, supplement or cosmetic product. It is not intended to diagnose, treat, cure or prevent any disease, and it is not for human or veterinary use. By purchasing, you confirm that the product will be used solely for lawful laboratory research.
5-Amino-1MQ 50mg FAQs
What is 5-Amino-1MQ?
5-Amino-1MQ is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) used in metabolism, NAD+ and adipocyte research.
Is 5-Amino-1MQ a peptide?
No. It is a quinolinium small molecule with a cation mass of approximately 159.2 Da.
How do I dissolve 5-Amino-1MQ 50mg?
It is soluble in water, DMSO and methanol. Check the salt form on the batch certificate when calculating molarity.
How is 5-Amino-1MQ 50mg tested?
Every batch is tested to ≥99% purity by HPLC, with identity confirmed by mass spectrometry, at an ISO 17025 accredited third-party laboratory.
How should 5-Amino-1MQ be stored?
Keep the sealed vial at −20°C, protected from light and moisture. Refrigerate working solutions at 2–8°C and use promptly.
Is 5-Amino-1MQ 50mg for human use?
No. It is supplied strictly for in-vitro laboratory research and is not for human or veterinary use.